17.09.2012

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Announcements / Press Releases

Kuwait Invests in the Fight Against Malaria [RBM Press Release] — (English)
The State of Kuwait has pledged to contribute US$3 million to the global fight against malaria through a grant to the Roll Back Malaria Partnership (RBM) Secretariat. This contribution comes at the behest of His Highness Sheikh Sabah Al-Ahmad Al-Jaber Al-Sabah to help coordinate the global response to a leading killer disease. In June 2012, the Kuwait Fund for Arab Economic Development also committed US$1 million to the RBM Partnership Secretariat to support the global malaria fight...

General Assembly Calls for Accelerated Efforts to Eliminate Malaria in Developing Countries, Particularly Africa, by 2015, in Consensus Resolution [UN] — (English)
A United Nations Malaria Resolution, led by the Permanent Mission of the Democratic Republic of Liberia on behalf of the UN Africa Group, was adopted by the General Assembly yesterday. With guidance from the RBM Partnership, the recommendations in the resolution urge governments, together with United Nations agencies, private organizations and foundations to accelerate efforts to achieve by 2015 the targets set in Roll Back Malaria's Global Malaria Action Plan (GMAP) and the Millennium Development Goals (MDGs)...

Global Fund Adopts New Approach to Funding Grants [The Global Fund] — (English)
New Model to Simplify Applications and Make Funding More Predictable...

Diverse countries are making rapid progress in child survival – UNICEF report [UNICEF] — (English)
Countries across the world are making rapid progress in reducing child deaths, demonstrating that it is possible to radically reduce child mortality over the span of two decades, a UNICEF report says today...

Countries across the world are making rapid progress in reducing child deaths, demonstrating that it is possible to radically reduce child mortality over the span of two decades, a UNICEF report says today [UN-IGME, UNICEG and WHO Joint press release] — (English)
An annual report by the UN Inter-agency Group for Child Mortality Estimation (UN-IGME) shows that in 2011, an estimated 6.9 million children died before their fifth birthday, compared to around 12 million in 1990. Rates of child mortality have fallen in all regions of the world in the last two decades – down by at least 50 per cent in Eastern Asia, Northern Africa, Latin America and the Caribbean, South-eastern Asia and Western Asia...

WHO Director-General addresses Europe's ministers of health [WHO] — (English)
Dr Margaret Chan, Director-General of the World Health Organization, Address to the Regional Committee for Europe, Sixty-second session Malta...

SARN updates on latest meetings [RBM SARN] — (English)
E8 Tecnical Committee Meeting Mission Report (Johannesburg, South Africa) 5-6 September, 2012; MAZAMO-mi Cross-Border Meeting report (Chipata, ZAMBIA) 13-14 August 2012; Report of the Annual Trans-Kunene Malaria Initiative (TKMI) Stakeholders Meeting (Ondjiva, Angola) 13-14 August 2012...

6th Case Management Working Group (CMWG) documents [RBM CMWG] — (English)
Agenda, list of participants, presentations...

WHO Malaria Rapid Diagnostic Test (RDT) Product Testing Programme [WHO] — (English)
WHO is now calling for expression of interest (EOI) for submission of antigen-detecting malaria rapid diagnostic tests to Round 5 of the WHO Malaria Rapid Diagnostic Test (RDT) Product Testing Programme. Expressions of interest must be received by 24 September 2012...

Call for Letters of Interest – Malawi and Mozambique [WHO/GMP] — (English)
The WHO Global Malaria Programme is calling for expressions of interest from Malawi and Mozambique under a new programme to scale up integrated community case management of malaria, pneumonia and diarrhea. The deadline for letters of interest is 21 September 2012...

Web Communications Consultant [WHO/GMP] — (English)
GMP is currently looking for a Web Communications Consultant to perform duties three days per week, starting as soon as possible. The contract will be issued for 6 months initially, on a renewable basis. Application deadline: 30 September 2012...

Intern, Human Resources [MMV] — (English)
MMV is looking for a talented person to join our HR team immediately (part-time or full time) for a six-month period (extendable). Application deadline: 23 September 2012..

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Articles requiring subscription or registration

Effect of intermittent preventive treatment for malaria during infancy on serological responses to measles and other vaccines used in the Expanded Programme on Immunization: results from five randomised controlled trials [The Lancet, Volume 380, Issue 9846, Pages 1001 - 1010, 15 September 2012 doi:10.1016/S0140-6736(12)60775-2] — (English)
IPTi with sulfadoxine-pyrimethamine does not affect serological responses to EPI vaccines. This analysis, therefore, supports the WHO recommendation for coadministration of IPTi with sulfadoxine-pyrimethamine to infants at the time of the second and third doses of DTP and measles vaccination, in areas of sub-Saharan Africa with moderate to high malaria transmission and where malaria parasites are sensitive to these drugs. It also suggests that treatment of clinical malaria at or around the time of vaccination does not compromise vaccine responsiveness...

Fighting neglected tropical diseases in the southern United States [BMJ 2012;345:e6112] — (English)
The World Health Organization, the World Bank, and professionals have advocated strongly for global programmes to deliver packages of essential drugs to treat the tropical diseases with the highest prevalence, such as tuberculosis and malaria, while simultaneously developing new or improved drugs and vaccines...

Relapses contribute significantly to the risk of P. vivax infection and disease in Papua New Guinean children 1-5 years of age [J Infect Dis. (2012) doi: 10.1093/infdis/jis580] — (English)
Even in highly endemic areas with a high risk of reinfection anti-hypnozoite treatment should be given to all cases with parasitologically confirmed Pv infections...

New insights into acquisition, boosting and longevity of immunity to malaria in pregnant women [J Infect Dis. (2012) doi: 10.1093/infdis/jis566] — (English)
These findings may have important practical implications for predicting the duration of vaccine-induced responses by candidate antigens and supports the development of malaria vaccines to protect pregnant women...

Changes in Anopheles funestus biting behaviour following universal coverage of long-lasting insecticidal nets in Benin [J Infect Dis. (2012) doi: 10.1093/infdis/jis565] — (English)
This study provides evidence for a switch in malaria vectors biting behaviour following the implementation of LLIN at universal coverage...

Seasonal prevalence of malaria vectors and entomological inoculation rates in the rubber cultivated area of Niete, South Region of Cameroon [Parasites & Vectors 2012, 5:197 doi:10.1186/1756-3305-5-197] — (English)
Mosquitoes were sampled by night collections on human volunteers, identified morphologically and members of the Anopheles gambiae complex further identified to species and molecular form. Parity status was determined following the dissection of the ovaries. Plasmodium falciparum circumsporozoite antigen indices were estimated after the identification of CS antigen by ELISA and the average entomological inoculation rates determined...

Dynamics of Plasmodium falciparum enoyl-ACP reductase and implications on drug discovery [Protein Science DOI: 10.1002/pro.2155] — (English)
Here we perform extensive molecular dynamics simulations of tetrameric PfENR in different states of cofactor and ligand binding, and with a variety of different ligands bound...

Antigenic Characterisation of an Intrinsically Unstructured Protein: Plasmodium falciparum Merozoite Surface Protein 2 [Infection and immunity, doi: 10.1128/​IAI.00665-12] — (English)
Further studies of the structural basis of these antigenic differences are required in order to optimize recombinant MSP2 constructs being evaluated as potential vaccine components...

Draft Genome Sequences of Enterobacter sp. Isolate Ag1 from the Midgut of the Malaria Mosquito Anopheles gambiae [J. Bacteriol. October 2012 vol. 194 no. 19 5481 doi: 10.1128/​JB.01275-12] — (English)
An isolate of Enterobacter sp. was obtained from the microbial community within the gut of the Anopheles gambiae mosquito, a major malaria vector in Africa. This genome was sequenced and annotated. The genome sequences will facilitate subsequent efforts to characterize the mosquito gut microbiome...

Draft Genome Sequence of Pseudomonas sp. Strain Ag1, Isolated from the Midgut of the Malaria Mosquito Anopheles gambiae [J. Bacteriol. October 2012 vol. 194 no. 19 5449, doi: 10.1128/​JB.01173-12] — (English)
A Pseudomonas sp. bacterium was isolated from the midguts of Anopheles gambiae mosquitoes. Here we present the annotated Pseudomonas sp. draft genome sequence as a contribution to the efforts of characterization of the mosquito gut microbiome...

Malaria infection and feather growth rate predict reproductive success in house martins [Oecologia] — (English)
We found a negative association between haemosporidian parasite infection status and inferred growth rate of tail feathers. A low feather growth rate and blood parasite infections were related to a delay in laying date in their European breeding quarters...