6.08.2012
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Announcements / Press Releases
RBM Roadmaps updates [RBM] — (English)
July and August updates...
Battling a Fatal Wave of Malaria in DRC [Doctors Without Borders] — (English)
A malaria outbreak has struck several regions of Orientale province in northwest Democratic Republic of Congo (DRC). In early June, Doctors Without Borders/Médecins Sans Frontières (MSF) sent an emergency team into the Ganga-Dingila health region, where approximately 118,000 people live in isolated, hard-to-reach communities that lack access to medical care...
Centres for Disease Control (CDC): Research Entomologist Position in Haiti [CDC] — (English)
Application deadline: 9 August 2012...
WHO WPRO: Medical Officer (Malaria, and other Vectorborne and Parasitic Diseases) [WPRO] — (English)
View vacancy notice from WPRO...
Senior Malaria Advisor or Project Management Specialist (Malaria) [USAID] — (English)
Solicitation Number: 617-12-0008, Location: Uganda USAID-Kampala...
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Articles requiring subscription or registration
Mapping the receptivity of malaria risk to plan the future of control in Somalia [BMJ Open 2012;2:e001160 doi:10.1136/bmjopen-2012-001160] — (English)Compared with maps of receptive risks, contemporary maps of transmission mask disparities of malaria risk necessary to prioritise and sustain future control. As malaria risk declines across Africa, efforts must be invested in measuring receptivity for efficient control planning...
Evaluation of antigen detection tests, microscopy, and polymerase chain reaction for diagnosis of malaria in peripheral blood in asymptomatic pregnant women in nanoro, burkina faso [Am J Trop Med Hyg. 2012 Aug;87(2):251-6] — (English)
Rapid diagnostics tests (RDTs) detect malaria specific antigen(s) in the circulation, even when parasites are sequestered in the placenta and not visible by microscopy...
Insecticide-Treated Plastic Sheeting for Emergency Malaria Prevention and Shelter among Displaced Populations: An Observational Cohort Study in a Refugee Setting in Sierra Leone [Am J Trop Med Hyg. 2012 Aug;87(2):242-50] — (English)
A double-blind phase III malaria prevention trial was conducted in two refugee camps using pre-manufactured insecticide-treated plastic sheeting (ITPS) or untreated polyethylene sheeting (UPS) randomly deployed to defined sectors of each camp...
Emerging Nucleic Acid-Based Tests for Point-of-Care Detection of Malaria [Am J Trop Med Hyg. 2012 Aug;87(2):223-30] — (English)
Malaria remains a serious disease in the developing world. There is a growing consensus that new diagnostics are needed in low-resource settings. The ideal malaria diagnostic should be able to speciate; measure parasitemia; low-cost, quick, and simple to use; and capable of detecting low-level infections. A promising development are nucleic acid tests (NATs) for the diagnosis of malaria, which are well suited for point-of-care use because of their ability to detect low-level infections and speciate, and because they have high sensitivity and specificity. The greatest barrier to NAT use in the past has been its relatively high cost, and the amount of infrastructure required in the form of equipment, stable power, and reagent storage. This review describes recent developments to decrease the cost and run time, and increase the ease of use of NAT while maintaining their high sensitivity and specificity and low limit of detection at the point-of-care...
Reductions in Artemisinin-Based Combination Therapy Consumption after the Nationwide Scale up of Routine Malaria Rapid Diagnostic Testing in Zambia [Am J Trop Med Hyg 2012 12-0127] — (English)
Results varied between districts, with significant reductions in low transmission areas but none in high areas. Rapid diagnostic tests may contribute to rationalization of treatment of febrile illness and reduce antimalarial drug consumption in Africa; however, their impact may be greater in lower transmission areas...
Molecular characterization of avian malaria parasites in three Mediterranean blue tit (Cyanistes caeruleus) populations [PARASITOLOGY RESEARCH 2012, DOI: 10.1007/s00436-012-3062-z] — (English)
We genetically analysed malaria parasites (Protozoa) in three Mediterranean blue tit (Cyanistes caeruleus) populations from central Spain...
Targets of antibodies against Plasmodium falciparum–infected erythrocytes in malaria immunity [J Clin Invest. doi:10.1172/JCI62182] — (English)
These findings advance our understanding of the targets and mediators of human immunity to malaria and have major implications for malaria vaccine development...
Severe Plasmodium vivax malaria among Sudanese children at New Halfa Hospital, Eastern Sudan [Parasites & Vectors 2012, 5:154 doi:10.1186/1756-3305-5-154] — (English)
Severe P. vivax malaria is an existing entity in eastern Sudan. Further studies are required to understand emergence of severe P. vivax malaria...
Malaria parasite signal peptide peptidase is an ER-resident protease required for growth but not invasion [Traffic, DOI: 10.1111/j.1600-0854.2012.01402.x] — (English)
Contrary to previous reports, these results demonstrate that PfSPP plays no role in erythrocyte invasion...