9.07.2012
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Announcements / Press Releases
Tunis Declaration Calls for Increased Domestic Financing for Health [RBM press release] — (English)
African Ministers of Finance and Health met in Tunis this week to review strategies for investing in the continent's health sector during the coming years. Addressing the ministers, the Roll Back Malaria Partnership's Board Chair, Victor Makwenge urged the uptake of public-health and financing policies that demonstrate impact on maternal and child health...
ASEAN political commitment critical to sustain malaria gains [RBM press release] — (English)
As the ten member countries gather at the ASEAN Health Ministerial Meeting, the Government of Thailand and the Roll Back Malaria Partnership (RBM) convene a high-level consultation during the event to urge greater political support for on-going malaria control efforts in the region...
Miss Senegal joins the Senegalese Red Cross in the fight against malaria [IFRC pess release] — (English)
To help raise the profile of the campaign, the Senegalese Red Cross bought in Penda Ly, Miss Senegal 2012, as its Goodwill Ambassador. In the field, she accompanies a team of 832 volunteers and 98 supervisors trained to raise awareness and distribute bed net with the aim of achieving universal coverage in many villages...
The Field Museum and Malaria Consortium to Unveil Photography Exhibition Highlighting Global Impact of Malaria [Malaria Consortium] — (English)
Malaria: blood, sweat and tears, an exhibition produced by award-winning US photographer Adam Nadel with international non-profit health organization, Malaria Consortium, opens tomorrow to the public at the Field Museum in Chicago. Nadel and colleagues from London-based Malaria Consortium will be joined by VIP guests from among Chicago's civic and business sectors, the University of Chicago and members of the medical community, at a preview event tonight at the Field Museum to celebrate the launch of the exhibit...
UNMC RESEARCHER LED DEVELOPMENT OF NEW MALARIA DRUG [UNMC News] — (English)
A powerful new drug to treat malaria – the invention of a University of Nebraska Medical Center College of Pharmacy researcher -- will help take the bite out of malaria...
MMV: Associate Director, Clinical Development [MMV] — (English)
Application deadline: 15 July 2012...
MMV: Intern, Human Resources [MMV] — (English)
Application deadline: 22 July 2012...
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Articles requiring subscription or registration
Make Mine Malaria [Am J Trop Med Hyg 2012 vol. 87 no. 1 193-194 doi: 10.4269/ajtmh.2012.12-0269] — (English)
Sometime in the 1990s, I started writing occasional book reviews for The Los Angeles Times...
Malaria Prophylaxis in Latin America: A Controversial Topic [Am J Trop Med Hyg 2012 vol. 87 no. 1 190-191 doi: 10.4269/ajtmh.2012.12-0193a] — (English)
We read the comprehensive review of Steinhardt and colleagues on malaria prophylaxis for travelers to Latin America with great interest. Still, because this subject is controversial in Travel Medicine, we would like to add some information from Germany, a country not cited by the review...
Reduction of Malaria Prevalence by Indoor Residual Spraying: A Meta-Regression Analysis [Am J Trop Med Hyg 2012 vol. 87 no. 1 117-124 doi: 10.4269/ajtmh.2012.11-0620] — (English)
This study reports the findings of a meta-regression analysis based on 13 published studies, which were chosen from more than 400 articles through a systematic search and selection process...
Community Health Workers Use Malaria Rapid Diagnostic Tests (RDTs) Safely and Accurately: Results of a Longitudinal Study in Zambia [Am J Trop Med Hyg 2012 vol. 87 no. 1 57-63 doi: 10.4269/ajtmh.2012.11-0800] — (English)
This study assessed CHW ability to use RDTs safely and accurately up to 12 months post-training...
Repeated Artemisinin-Based Combination Therapies in a Malaria Hyperendemic Area of Mali: Efficacy, Safety, and Public Health Impact [Am J Trop Med Hyg 2012 vol. 87 no. 1 50-56 doi: 10.4269/ajtmh.2012.11-0649] — (English)
We conducted a randomized trial comparing artemether-lumefantrine, artesunate plus amodiaquine (AS+AQ) and artesunate plus sulfadoxine-pyrimethamine (AS+SP) in patients 6 months of age and older with uncomplicated malaria in Mali from July 2005 to July 2007...
Serious and Fatal Illness Associated with Falciparum and Vivax Malaria among Patients Admitted to Hospital at West Sumba in Eastern Indonesia [Am J Trop Med Hyg 2012 vol. 87 no. 1 41-49 doi: 10.4269/ajtmh.2012.11-0577] — (English)
Plasmodium vivax was associated with a substantial share of the burden of morbidity and mortality caused by malaria in this hypo- to meso-endemic community...
Pharmacokinetics of Piperaquine in Pregnant Women in Sudan with Uncomplicated Plasmodium falciparum Malaria [Am J Trop Med Hyg 2012 vol. 87 no. 1 35-40 doi: 10.4269/ajtmh.2012.11-0410] — (English)
The overall pharmacokinetic properties of piperaquine in this study were consistent with previously published reports in non-pregnant patients...
No Evidence of Delayed Parasite Clearance after Oral Artesunate Treatment of Uncomplicated Falciparum Malaria in Mali [Am J Trop Med Hyg 2012 vol. 87 no. 1 23-28 doi: 10.4269/ajtmh.2012.12-0058] — (English)
We provide baseline surveillance data for the emergence or dissemination of P. falciparum resistance in sub-Saharan Africa...
No Evidence of Decreased Artemisinin Efficacy in a High-Transmission Malaria Setting in Mali [Am J Trop Med Hyg 2012 vol. 87 no. 1 16-17 doi: 10.4269/ajtmh.2012.12-0344] — (English)
In this issue of the American Journal of Tropical Medicine and Hygiene, the work by Maiga and others15 reports a detailed clinical study to test whether resistance to artemisinins may be emerging in a high-transmission setting in Africa after several years of ACT use. This finding was achieved by comparing the therapeutic efficacy of the artemisinin-derivative artesunate, used as a monotherapy agent, between clinical trials in 2010–2011 and 2002–2004...
Quinine interactions with tryptophan and tyrosine in malaria patients, and implications for quinine responses in the clinical setting [J. Antimicrob. Chemother. (2012) doi: 10.1093/jac/dks253] — (English)
Plasma quinine levels during therapy are related to patient tryptophan and tyrosine levels, and these interactions can determine patient responses to quinine. The study also highlights the potential for extrapolating insights directly from the yeast model to human malaria patients...
Imported Plasmodium falciparum malaria in the United States [Am J Health Syst Pharm July 15, 2012 69:1186-1187] — (English)
By Kennedy WK, Berg AM...
Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite [Traffic DOI: 10.1111/j.1600-0854.2012.01394.x] — (English)
Rhoptries are specialized secretory organelles characteristic of single cell organisms belonging to the clade Apicomplexa...
Enhanced basophil reactivities during severe malaria and their relationship with the plasmodial histamine releasing factor PfTCTP [IAI.00072-12 doi: 10.1128/IAI.00072-12] — (English)
Our results show an association between basophil reactivity, malaria severity and suggest a pathogenic role for the plasmodial PfTCTP in the induction of this allergy-like mechanism...
Diagnosis, clinical presentation and in-hospital mortality of severe malaria in HIV co-infected children and adults in Mozambique [Clin Infect Dis. (2012) doi: 10.1093/cid/cis590] — (English)
Severe falciparum malaria with HIV co‐infection is common in settings with a high prevalence of both diseases, but there is little information whether HIV affects the clinical presentation and outcome of severe malaria...
Thrombotic microangiopathy and acute kidney injury following vivax malaria [Clinical and Experimental Nephrology Volume 1 / 1997 - Volume 16 / 2012] — (English)
This observational study includes patients referred to a tertiary care center in North India during June to September 2011 with severe AKI, anemia, and thrombocytopenia following vivax malaria. Renal biopsies were processed by light, immunofluorescence, and electron microscopy...