11.06.2012
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Announcements / Press Releases
RBM's MERG meeting focuses on tools to track progress in malaria control [RBM] — (English)
The Roll Back Malaria Monitoring and Evaluation Reference Group (RBM MERG) held its 19th meeting to track GMAP objectives, targets and milestones and review use of malaria monitoring tools at sub-national level. In addition to providing a platform for information-sharing and coordination, the meeting allowed participants to review ongoing work and discuss priorities to be addressed in the 2013 workplan...
The Kuwait Fund to support RBM in its mission to end malaria [RBM] — (English)
The Kuwait Fund for Arab Economic Development pledged this week to contribute 1 million US$ over a period of 3 years to the activities of the Roll Back Malaria Partnership Secretariat. The funding will help strengthen high-level political commitment for the fight against malaria...
UNICEF to save $22 million through transparency in buying bed nets [UNICEF] — (English)
UNICEF Executive Director Anthony Lake said today that a more transparent and competitive market will lead to savings of more than US$20 million over the next 12 months through a price reduction of 20 per cent for bed nets that protect people from malaria...
United Nations Foundation and Virgin Produced Take Social Good to New Heights [UN Foundation] — (English)
Partnership highlights key global issues through dynamic PSAs on all Virgin America flights...
Anti-Malaria Effort Gets Results That Must Be Maintained [U.S. Department of State IIP Digital] — (English)
An independent evaluation team finds that the President's Malaria Initiative (PMI) has been "very successful" in reducing children's deaths from the mosquito-borne parasitic disease, but also warns that the program must gear up if those gains are to be sustained...
Vector Control Working Group (VCWG) updates [RBM VCWG] — (English)
Minutes of the 3rd Meeting of Insecticide Resistance Work Stream; Report of the 3rd Meeting of the Outdoor Malaria Transmission Work Stream; Report of 5th Meeting of Continuous LLIN Distribution Systems Work Stream ; Report of the 3rd Meeting of Durability of LLINs in the field Work Stream ; Report of the 3rd Meeting of Capacity Building for IRS Work Steam ; Report of the 3rd Meeting of Larval Source Management Work Stream ; Report of the 4th Meeting of the Optimizing Evidence for Vector Control Interventions Work Stream ; Report of the 4th Meeting of the Entomological Monitoring and IVM Work Stream...
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Articles requiring subscription
Combination of malaria vector control interventions in pyrethroid resistance area in Benin: a cluster randomised controlled trial [The Lancet Infectious Diseases, doi:10.1016/S1473-3099(12)70081-6] — (English)
We did a cluster randomised controlled trial in 28 villages in southern Benin, west Africa...
Indoor residual spraying for prevention of malaria [The Lancet Infectious Diseases, doi:10.1016/S1473-3099(12)70139-1] — (English)
Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the two primary vector control interventions for malaria prevention. Use of LLINs in malaria endemic sub-Saharan Africa has, with support from the Global Fund and other international agencies, become much more common in the past decade...
Towards ending preventable child deaths [The Lancet, Volume 379, Issue 9832, Pages 2119 - 2120, doi:10.1016/S0140-6736(12)60908-8] — (English)
The number of deaths among children younger than 5 years has declined from more than 12 million in 1990 to 7·6 million in 2010. The mortality rate in children under 5 years has dropped from 88 deaths per 1000 livebirths in 1990 to 57 in 2010—a 35% reduction.2 The rate of decline in the under 5 mortality rate has accelerated from 1·9% a year from 1990 to 2000 to 2·5% a year from 2000 to 2010. ...
Evolutionary selection of enzymatically synthesized semiconductors from biomimetic mineralization vesicles [PNAS] — (English)
Here, we present a cell-free synthetic biological platform to advance studies of biologically synthesized solid-state materials...
Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese [Genes and Immunity advance online publication 7 June 2012; doi: 10.1038/gene.2012.25] — (English)
In summary, variants in six genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese...
Force of infection is key to understanding the epidemiology of Plasmodium falciparum malaria in Papua New Guinean children [doi: 10.1073/pnas.1200841109 PNAS June 4, 2012] — (English)
This study was designed to test whether molFOI influenced the risk of clinical malaria episodes and how far molFOI reflected environmental determinants of transmission, such as seasonality and small-scale geographical variation or effects of insecticide-treated nets (ITNs)...
Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi [doi: 10.4269/ajtmh.2012.11-0621 Am J Trop Med Hyg 2012 vol. 86 no. 6 997-1004] — (English)
We evaluated the impact of IRS on parasitemia and anemia prevalence in children less than five years of age by using a cross-sectional household survey conducted in 2009, six months after the second IRS spray round...
PFE0565w, a Plasmodium falciparum Protein Expressed in Salivary Gland Sporozoites [doi: 10.4269/ajtmh.2012.11-0797 Am J Trop Med Hyg 2012 vol. 86 no. 6 943-954] — (English)
The Plasmodium falciparum gene, PFE0565w, was chosen as a candidate for study based on data from PlasmoDB, the Plasmodium database, indicating that it is expressed both at the transcriptional and protein levels in sporozoites, likely encodes a putative surface protein, and may have a potential role in the invasion of host tissues...
Use of a Rhesus Plasmodium cynomolgi Model to Screen for Anti-Hypnozoite Activity of Pharmaceutical Substances [doi: 10.4269/ajtmh.2012.11-0552 Am J Trop Med Hyg 2012 vol. 86 no. 6 931-935] — (English)
The rhesus macaque–P. cynomolgi model remains a useful tool for screening drugs with anti-hypnozoite activity. Tinidazole and pyrazinamide require further investigation as agents to enable dose reduction of primaquine...
Contributions of Polyclonal Malaria, Gametocytemia, and Pneumonia to Infant Severe Anemia Incidence in Malaria Hyperendemic Pemba, Tanzania [doi: 10.4269/ajtmh.2012.11-0164 Am J Trop Med Hyg 2012 vol. 86 no. 6 925-930] — (English)
In an observational, longitudinal study of two cohorts of about 300 infants followed-up for six months in a malaria hyperendemic area, the risk factors for severe anemia incidence were clinical malaria and pneumonia, which outweighed nutritional and sociodemographic factors...
Adolescent pregnancy and the risk of Plasmodium falciparum malaria and anaemia-a pilot study from Sekondi-Takoradi metropolis, Ghana [Acta Tropica] — (English)
The present study aimed at evaluating the prevalence of Plasmodium falciparum and anaemia infection in adolescent pregnant girls in the Sekondi-Takoradi metropolis, Ghana...
Malaria Parasite Type 4 Equilibrative Nucleoside Transporters (ENT4) are Purine Transporters with Distinct Substrate Specificity [Biochem. J. (2012) Immediate Publication, doi:10.1042/BJ20112220] — (English)
ENT4 is a purine transporter with unique substrate and inhibitor specificity. Its role in parasite physiology remains uncertain but is likely significant because of the strong conservation of ENT4 homologues in Plasmodia genomes...
Antenatal Receipt of Sulfadoxine-Pyrimethamine Does Not Exacerbate Pregnancy-Associated Malaria Despite the Expansion of Drug-Resistant Plasmodium falciparum: Clinical Outcomes From the QuEERPAM Study [Clin Infect Dis. (2012) 55(1): 42-50 doi:10.1093/cid/cis301] — (English)
Antenatal preventive administration of sulfadoxine-pyrimethamine did not potentiate pregnancy-associated malaria morbidity despite expansion and fixation of drug-resistant malaria parasites. Sulfadoxine-pyrimethamine may be a safe component of malaria prevention programs without causing adverse effects on birth outcomes...
Efficacy of sunlight-activatable porphyrin formulates on larvae of Anopheles gambiae M and S molecular forms and An. arabiensis: a potential novel biolarvicide for integrated malaria vector control [Acta Trop. 2012 Jun 2] — (English)
In order to validate the approach for the control of the malaria vector, we tested the photo-larvicidal activity of a novel porphyrin, namely meso-tri(N-methyl-pyridyl), mono(N-dodecyl-pyridyl)porphine, C12, associated with two specifically selected carriers, against Anopheles gambiae s.s. and An. arabiensis larvae, both laboratory reared and collected from malaria endemic sites in Burkina Faso...