13.02.2012
Read this issue and previous issues online.
Announcements / Press Releases
Confederation of African Football Endorses United Against Malaria Campaign During 2012 Orange Africa Cup of Nations [UAM Press Release] (English)
During the final week of the 2012 Orange Africa Cup of Nations, the Confederation of African Football (CAF) committed its support to the fight against malaria by officially endorsing the United Against Malaria (UAM) campaign. CAF’s president, Mr. Issa Hayatou, expressed his support for football’s role in educating fans about malaria prevention and treatment and, as part of global efforts to end malaria deaths, called on all CAF members to join UAM and raise awareness about the devastating disease...
RBM eNewsletter [RBM] (English)
February issue...
Award: Healthcare Engagement Strategy 2012 'Life Changer' [Healthcare Engagement Strategy] (English)
"Swaziland is a country that is transitioning from control to elimination of malaria", Simon Kunene, Manager of the National Malaria Control Programme in Swaziland tells me. And he should know – from his office he can plot the precise location of every confirmed case of malaria and every intervention put in place by health workers on the ground throughout the country. The GIS (Geographic Information System) platform he uses is part of a tracking and monitoring system that uses SMS messaging via mobile phones, GPS navigation, and data from multiple government departments to win the battle against this killer disease...
"Test and Treat" Model Offers New Strategy for Eliminating Malaria [Johns Hopkins Bloomberg School of Public Health] (English)
In a new study, researchers at the Johns Hopkins Malaria Research Institute found that a strategy of actively identifying undiagnosed malaria and then treating those with the disease resulted in significantly lower prevalence of malaria cases compared to a control group. Their findings are published in the February 3 edition of the journal PLoS ONE...
Malaria - Through the eyes of a child [BestNet] (English)
Bestnet is proud to introduce Malaria - Through the eyes of a child, a new book which documents our activities in celebration of World Malaria Day 2011. This year, Bestnet and our partners reached out to educate hundreds of school children on 5 continents about malaria and the protection provided by sleeping under our Netprotect® LLINs. The children were asked to inform us about the devastating effects of this life-threatening disease through their own poems, stories and drawings. The children's thoughts and illustrations were so insightful, dramatic and touching that we have chosen to share them by compiling them into a book that can be treasured by many...
DNDi News [DNDi] (English)
February 2012 issue...
Friends Africa Newsletter [Friends Africa ] (English)
February issue...
ACT Consortium Policy Liaison Coordinator [Artemisinin Combination Therapy (ACT) Consortium] (English)
Application deadline: 4 March 2012...
MMV: Intern, External Relations [MMV] (English)
Application deadline: 19 February 2012...
Health Policy Action Fund : Call for Proposals [HPAF] (English)
View job description on the HPAF website Proposals can be sent to cjacob@oxfam.org.uk...
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Articles requiring subscription
Death toll from malaria is double the WHO estimate, study finds [BMJ 2012; 344 doi: 10.1136/bmj.e895] (English)
The World Health Organization has defended its figures on malaria mortality after a study found that the number of deaths from the disease had been seriously underestimated...
MK-4815: A Potential New Oral Agent for the Treatment of Malaria [AAC.05326-11 2012, doi: 10.1128/AAC.05326-11] (English)
The attractive biological and pharmaceutical profile of MK-4815 demonstrates the potential for its use in combination with other agents in the fight against malaria...
Comparative efficacy of Artemisinin Combination Therapies (ACTs) in P. falciparum malaria and polymorphism of PfATPase6, Pfcrt, Pfdhfr and Pfdhps genes in tea gardens of Jalpaiguri district, India [AAC.05388-11 2012, doi: 10.1128/AAC.05388-11] (English)
The efficacy of this ACT needs periodical monitoring. Artemether-Lumefantrine and Artesunate-Mefloquine are effective alternatives to Artesunate-Sulfadoxine-Pyrimethamine combination...
Ronald Ross' opposition to Battista Grassi's malaria research [J Med Biogr November 2011 19:184;] (English)
By Cook GC....
Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults [J. Antimicrob. Chemother. (2012) doi: 10.1093/jac/dkr596] (English)
We investigated the pharmacokinetics of artemether, dihydroartemisinin and lumefantrine after administration of a single dose of 80/480 mg of artemether/lumefantrine to HIV-infected adults, taken with and without lopinavir/ritonavir...
Antimalarial Effects of Iranian Flora Artemisia sieberi on Plasmodium berghei In Vivo in Mice and Phytochemistry Analysis of Its Herbal Extracts [Malaria Research and Treatment Volume 2012 (2012), Article ID 727032, 8 pages doi:10.1155/2012/727032] (English)
The aim of this study is pharmacochemistry of Iranian flora Artemisia sieberi and its antimalarial effects on Plasmodium berghei in vivo...
Medicinal Plants Used by Various Tribes of Bangladesh for Treatment of Malaria [Malaria Research and TreatmentVolume 2012 (2012), Article ID 371798, 5 pages doi:10.1155/2012/371798] (English)
The objective of the present study was to conduct an ethnomedicinal survey among various tribes of Bangladesh to identify the plants that they use for treatment of the disease...
Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy [European Journal of Drug Metabolism and Pharmacokinetics DOI: 10.1007/s13318-012-0080-2] (English)
We synthesized most of the known metabolites of ketotifen and evaluated their antimalarial activity and pharmacokinetics in mice...
Human erythrocyte remodelling during Plasmodium falciparum malaria parasite growth and egress [British Journal of Haematology, DOI: 10.1111/j.1365-2141.2012.09044.x] (English)
Here we review these cellular and molecular changes, which might not only sustain parasite growth but also prepare, at a very early stage, the last step of egress from the host cell...
Female Anopheles gambiae antennae: increased transcript accumulation of the mosquito-specific odorant-binding-protein OBP2 [Parasites & Vectors 2012, 5:27 doi:10.1186/1756-3305-5-27] (English)
Phylogenetic analysis indicates that its orthologs are present across culicid mosquitoes and are likely to play a conserved role in recognizing a molecule that might be critical for female behavior...

